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Drugs to be avoided or Used with Caution in Breast-feeding

 

Drugs

Comments

  Barbiturates Avoid if possible Large doses may produce drowsiness.
  Benzodiazepines Avoid repeated doses; lethargy and weight loss may occur in infant.
Bromide salts Avoid; sedation and rash in infant
   Chloral hydrate,
 Dichloralphenazone		 Sedation in infant.
   Meprobamate Concentration in milk may exceed maternal plasma concentrations fourfold and may cause drowsiness in infant.
(b) Antipsychotic drugs  
  Haloperidol Amount excreted in milk probably too small to be harmful.
  Lithium salts Monitor infant for possible intoxication; low incidence of adverse effects but increased by continuous ingestion. Good control of maternal plasma concentrations minimises the risk.
   Phenothiazine derivatives As for haloperidol, but drowsiness has been reported with chlorpromazine
(c)  Analgesics  
   Narcotic analgesics  
   Diamorphine, Morphine Therapeutic doses are unlikely to affect infant. Withdrawal symptoms occur in infants of dependent mothers. Breast-feeding is no longer considered best method of treating dependence in offspring of dependent mothers and should be stopped
   Methadone Withdrawal symptoms in infant; breast-feeding permissible during maintenance dosage


 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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