|
Drugs
|
Comments
|
| 1. Gastro-Intestinal system |
|
| Atropine |
May possibly have anticholinergic
effects in infants |
| Laxatives |
|
|
Anthraquinones |
Avoid; large doses may
cause increased gastric motility and diarrhoea, particularly
cascara and danthron |
| Phenolphthalein |
Avoid; increased gastric motility,
diarrhoea, and possibly rashes |
| 2.Cardiovascular system |
|
| Amiodarone |
Avoid. Present in milk significant
amounts. |
Beta
- adrenoceptor bloking
drugs |
Monitor infant; possible toxicity
due to beta blockade but amount of most beta-blockers excreted
in milk is too small to affect infant. |
| Oral
anticoagulants |
Risk of haemorrhage;
increased by vitamin-K deficiency. Warfarin appears safe but
some authorities consider breast-feeding is contraindicated
during therapy. Phenindione should be avoided. |
| 3. Respiratory system |
|
| Aminophylline |
Irritability in infant has
been reported. |
| Clemastine |
Drowsiness in infant has been
reported. |
Cough
mixtures containing
iodides |
Use alternative cough mixtures. |
| Ephedrine,
Pseudoephedrine |
Irritability and disturbed
sleep reported with ephedrine. Significant amounts of pseudoephedrine
in milk. |
| 4.Central nervous system |
|
|
(a) Hypnotics and sedatives |
|
|
Alcohol |
Large amounts may affect infant. |
