| Description
Tonoferon
Syrup
is a comprehensive preparation containing iron in colloidal
form and essential haematopoietic factors-Vitamin B12
& Folic Acid along with Lysine for normal growth and its maintenance
in children.
Composition
| Each ml (approx.
20 drops from the dropper) contains : |
|
|
| Colloidal Iron |
|
|
| equivalent to
elemental iron 25 mg |
|
|
| Lysine Hydrochloride
USP |
200 |
mg |
| Vitamin B12
IP |
5 |
µg |
| Folic Acid IP |
200 |
µg |
| Syrup and flavour
q.s. |
|
|
| Extra vitamins
added to compensate probable loss on storage. |
|
|
| For Paediatric
use. |
|
|
Actions
Inadequacy of iron in the diet is best reflected in the high
prevalence of anaemia and supplementation of iron is therefore
desired. Tonoferon
Drops has colloidal ferric hydroxide which provides the highest
amount of elemental iron (52.26%) of the commonly available
oral iron preparations. The iron in Tonoferon
Drops being in the colloidal form, undergoes ready conversion
into soluble form by the action of gastric acid and is easily
reduced to ferrous form by mucoproteins available in the secretions
of the stomach and small intestine along with other constituants
like succinic acid and ascorbic acid, assuring its greater
and better absorption with minimal gastric irritation resulting
in greater acceptability, particularly in children.
|
Both
vitamin B12 and folic acid in Tonoferon
Drops,
help cell metabolism, DNA synthesis and normal haemopoiesis.
Deficiencies of both vitamin B12 and folic acid
are common due to dietary inadequacies and particularly to
infants born to mothers who are grossly deficient in folate
or vitamin B12 during pregnancy. Supplementation
of both folic acid and vitamin B12 is therefore
necessary in such cases to prevent nutritional megaloblastic
anaemia. Lysine provides dietary supplement, increasing appetite
and weight gain in children
Indications
Tonoferon
Drops
is useful for the treatment of common iron deficiency anaemia
associated with dietary inadequacy in children. To provide
dietary supplementation for rapid growth and weight gain in
children and also for improving general metabolism and increasing
appetite.
Contraindications
Patients
with pernicious anaemia; hypersensitivity to any of the ingredients.
Adverse
Reactions
Mild
gastric intolerance may occur in iron sensitive patients.
Precautions
Underlying
causes should be determined in cases where anaemia exists.
Folic acid may mask the presence of pernicious anaemia due
to reversal of blood picture to normal but not affecting the
progression of neurological manifestations. In those with
conditions tending to vitamin B12 depletion, serum
B12 level should be regularly assessed during therapy
and in children with vitamin B12 deficiency concomitant
parenteral vitamin B12 therapy may be necessary
Drug
Interactions
Concomitant
therapy with antacids diminishes iron absorption. On concomitant
administration of iron and tetracycline the absorption of
both the drugs is markedly reduced leading to diminished therapeutic
effectiveness
Dose
Infants
less than one year : 5 drops twice daily.
Children
above 1 year : 10 drops twice daily.
Packing
Phials
15 ml
|
