| Description
Tonoferon
Syrup
is a comprehensive preparation containing iron in colloidal
form and essential haematopoietic factors-Vitamin B12
& Folic Acid along with Lysine for normal growth and its
maintenance in children.
Composition
| Each 5 ml contains :
|
|
|
| Colloidal Iron |
|
|
| equivalent to
elemental iron 80 mg |
|
|
| Vitamin B12
IP |
2 |
µg |
| Folic Acid IP |
200 |
µg |
| Syrup and flavour
q.s. |
|
|
| Extra vitamins
added to compensate probable loss on storage. |
|
|
Actions
Inadequacy of iron in the diet is best reflected in the high
prevalence of anaemia and supplementation of iron is therefore
desired. Tonoferon
Drops has colloidal ferric hydroxide which provides the highest
amount of elemental iron (52.26%) of the commonly available
oral iron preparations. The iron in Tonoferon
Drops being in the colloidal form, undergoes ready conversion
into soluble form by the action of gastric acid and is easily
reduced to ferrous form by mucoproteins available in the secretions
of the stomach and small intestine along with other constituants
like succinic acid and ascorbic acid, assuring its greater
and better absorption with minimal gastric irritation resulting
in greater acceptability, particularly in children.
Both
vitamin B12 and folic acid in Tonoferon
Syrup
,
help cell metabolism, DNA synthesis and normal haemopoiesis.
Deficiencies of both vitamin B12 and folic acid
are common due to dietary inadequacies and particularly to
infants born to mothers.
|
who
are grossly deficient in folate or vitamin B12
during pregnancy. Supplementation of both folic acid and vitamin
B12 is therefore necessary in such cases to prevent
nutritional megaloblastic anaemia. Lysine provides dietary
supplement, increasing appetite and weight gain in children
Indications
Tonoferon
is useful for the treatment of common iron deficiency anaemia
associated with dietary inadequacy, convalescence; anaemia
frequently observed in old age and adolescence, in women from
menarche to menopause, menorrhagia; microcytic or macrocytic
anaemia of pregnancy; dimorphic anaemia associated with blood
loss during surgery; chronic blood loss in bleeding piles;
chronic infections like tuberculosis, malaria, hepatic diseases
and increased body need in certain physiological conditions.
Contraindications
Patients
with pernicious anaemia; hypersensitivity to any of the ingredients.
Adverse Reactions
Mild
gastric intolerance may occur in iron sensitive patients.
Precautions
Underlying causes should be determined in cases where anaemia
exists. Folic acid may mask the presence of pernicious anaemia
due to reversal of blood picture to normal but not affecting
the progression of neurological manifestations. In those with
conditions tending to vitamin B12 depletion, serum
B12 level should be regularly assessed during therapy
and in children with vitamin B12 deficiency concomitant
parenteral vitamin B12 therapy may be necessary
Drug Interactions
Concomitant therapy with antacids diminishes iron absorption.
On concomitant administration of iron and tetracycline the absorption
of both the drugs is markedly reduced leading to diminished
therapeutic effectiveness
Dose
6 - 12 years : 5 ml twice daily after meals.
Packing
Phials
100 ml
|
